Health evidence reviews

Health evidence reviews and research influences new health technologies and services and optimizes existing ones.

Health technology assessments

Health evidence reviews use a research method called health technology assessment. This research is done to help determine what health care technologies, services, and models of care are suitable and sustainable for a given population.

Health evidence reviews can capture information on effectiveness, safety, cost-effectiveness, real-world practices and budget impact, as well as the ethical, social, legal and policy implications on the health care system.

Improving health care services

Health evidence reviews are used to inform health system decision-makers and improve planning. Reviews provide balanced evidence, critical analysis, and an Alberta perspective to help decision-makers tackle problems in the health care system, and make progress on Alberta’s health care priorities.

Reviews examine how health care services can be delivered better in a certain part of the health care system, or for a specific disease or condition. This is preferred to evaluating individual technologies and services for adoption.

Reviews provide evidence for a health system decision-maker or planner who is willing and able to use the results to make change.

Health evidence review framework

Read the 2017 Health Evidence Review Framework

How health evidence review topics are identified

Open nomination

Health care professionals, planners, and stakeholders who need evidence to tackle a health system problem or task should contact us to request a review.

Targeted consultation

The Ministry of Health consults planners and decision-makers who are working on the health care system’s priorities to identify problems or challenges that could benefit from a health evidence review.

Since 2018, proposals have been requested that focus on working with stakeholders to provide evidence required to create innovative care models, disease pathways and/or transitions of care.

These proposals are screened by representatives from the Ministry of Health and Alberta Health Services, and then validated by a committee of senior health system leaders.

Assessing existing inefficiencies

Health evidence reviews use peer-reviewed studies, reports, interviews, as well as data collected across the health care system to identify duplication, waste, gaps in care, or areas of low efficiency that could be improved using an evidence-informed approach.

Screening and prioritization for review

Every topic identified is considered to determine if it will benefit from an Alberta health evidence review. The selection process tries to answer the following questions:

  • Is the review topic considered high-priority for the Alberta government and health care system?
  • Will the review have a wide reaching and or significant impact on how care is delivered?
  • Is there pressure for change?
  • Is there willingness to change?
  • Is there a health system decision-maker who will use review results to affect change?
  • What is the likelihood that change will happen?

Health evidence review partners

The Ministry of Health collaborates with these internationally recognized health technology assessments experts to conduct reviews in an arms-length capacity:

Health evidence review products

Every review is designed to meet the needs of the health system client. Reviews can be customized to provide a range of evidence and information, including:

  • systematic reviews of effectiveness and safety
  • cost-effectiveness analyses
  • budget impact analyses
  • real-world evidence
  • implementation feasibility assessments
  • environmental scans
  • policy analyses

The conclusions presented in the reports are solely those of the partner organizations that produced the reports and do not represent the policies or position of the Alberta government or any other agency. Updates are provided when available.

Advice from high-level health care leaders

The Alberta Advisory Committee on Health Technologies provides direction and a broader health system perspective to Alberta’s health evidence reviews.

Members of the committee include senior leaders from the Ministry of Health and Alberta Health Services (co-chairs), as well as senior representatives from the Alberta Medical Association, the College of Physicians and Surgeons of Alberta, the College and Association of Registered Nurses of Alberta, and Canada’s Medical Technology Companies.

The committee:

  • advises on whether potential review topics are timely and a good fit for health system priorities
  • provides the perspectives of leaders from across the health care system on how best to use review findings to achieve change

Knowledge translation support

The Ministry of Health can help clients communicate review findings to relevant audiences and stakeholders to build support for change. The ministry and its health evidence review partners offer customized reports and summary documents, presentation and publicity materials, educational tools and seminars, and other knowledge translation supports for specific audiences.

Implementation supports

Every review is selected, planned, and conducted with careful consideration for whether and how the results can be used to inform improvements in the health care system. Before starting any review, there must be a strong degree of certainty that the review findings can and will be used to affect change.

As part of the health evidence review process, the Ministry of Health and the partner conducting the review work with the client and other health system stakeholders to understand:

  • possible outcomes from the review
  • how these outcomes could be used to achieve changes in care delivery (possible implementation approaches)
  • whether change is feasible
  • what impacts this change could have on Albertans and the health care system

If requested, an optimal implementation approach can be proposed and developed using information obtained through evidence gathering, data modelling, health system capacity analysis, and consultation.

Health evidence reviews

Featured health evidence review

Review: Endovascular Therapy for Ischemic Stroke

  • Conducted by – Institute of Health Economics
  • Client – Endovascular Therapy Provincial Implementation Working Group
  • Objective – To determine how best to provide endovascular therapy for ischemic stroke in Alberta.
  • Methodology – Systematic literature reviews, grey literature review, consultation with expert advisory group, economic analysis, and modelling.
  • Findings – The optimal model for providing endovascular therapy in Alberta combine two treatment and transportation strategies based on the geographical location of stroke onset.
  • Outcome – A new provincial endovascular therapy delivery model was designed to optimize care based on the geographic location of stroke onset.

Ongoing provincial health evidence reviews

Current and ongoing health evidence review reviews are:

  • Assisted Peritoneal Dialysis within Alberta
  • The Role of Select Diabetes Technologies in the Care Pathway for Insulin-Treated Diabetes
  • Strategies to Improve Access to Surgical Care in Alberta
  • Designing the Future of Stroke Rehabilitation in Alberta
  • Interventions to Decrease Risk Factors associated with Vascular Disease
  • The Effectiveness and Cost-Effectiveness of Oncotype Dx and Prosigna Genetic Testing in Early-Stage Breast Cancer

Completed provincial health evidence reviews


Glucose Monitoring Technologies for the Management of Insulin-dependent Diabetes

Optimizing Stroke Rehabilitation Practice in Alberta: Evidence Synthesis and Economic Evaluation

Urgent Care Models to Bridge Emergency and Primary Care

Measuring Access to Specialty Care: A Health Evidence Review

Optimizing Vascular Risk Reduction Initiatives in Alberta: A Clinical Review and Economic Analysis


Clinical Effectiveness and Cost-effectiveness of Oncotype DX and Prosigna Genetic Testing in Early-stage Breast Cancer

Strategies to Improve Access to Surgical Care: An Evidence Review


Palliative and End of Life Care: A Health Technology Assessment


Robot-Assisted Laparoscopic Prostatectomy

Robot-Assisted Partial Nephrectomy for Renal Cell Carcinoma

Transoral Robotic Surgery

Endovascular Therapy For Ischemic Stroke

Community Paramedicine Evidence Synthesis

Cannabis Evidence Series


Assisted Reproductive Technologies (2016) – Addendum to the 2014 STEP Report

Fixed Ex Vivo Lung Perfusion

Hepatitis C Screening in Alberta: a Health Technology Assessment (2016)

Insulin Pump Therapy Access with Evidence Development

Newborn Blood Spot Screening for galastosemia, tyrosinemia type I, homocystinuria, sickle cell anemia, sickle cell/beta-thalassemia, sickle cell/hemoglobin C disease, and severe combined immunodeficiency (2016)


Assisted Reproductive Technologies (2014)

Appropriate Use of Antipsychotics in Long-Term Care Facilities (2014)

Endovenous Ablation Interventions for Symptomatic Varicose Veins of the Legs (2014)

First and Second Trimester Screening Update – Final STE Report (2014)

Hysteroscopic Tubal Sterilization (2014)

Low Dose Computed Tomography (LDCT) for the Screening of Lung Cancer in Adults (2014)

Renal Denervation for Treatment Resistant Hypertension (2014)

Repetitive Transcranial Magnetic Stimulation for Treatment Resistant Depression (2014)


Level I and Level III Sleep Studies for the Diagnosis of Sleep Disordered Breathing (SDB) in Adults (2013)

Total Prosthetic Replacement of the Temporomandibular Joint: A Rapid Evidence Assessment and Economic Analysis (2013)

Islet Transplantation for the Treatment of Type 1 Diabetes (2013)

Use of Oncotype DX for Guiding Adjuvant Chemotherapy Decisions in Early Stage Invasive Breast Cancer Patients in Alberta (2013)


Bariatric Treatments for Adult Obesity (2012)

Corneal Cross-Linking for Keratoconus and Other Corneal Thinning Disorders (2012)

Transient Elastography in Liver Disease (2012)

Robot-assisted Surgery for Prostatectomy and Hysterectomy: A Review of the Clinical and Cost-Effectiveness – An Update (2012)

Insulin Pump Therapy for Type 1 Diabetes (2012)

First and Second Trimester Prenatal Screening for Trisomies 13, 18, and 21 and Open Neural Tube Defects (2012)

The Effectiveness and Safety of Preschool Hearing Screening Programs (2012)

The Safety and Effectiveness of Preschool Vision Screening (2012)

Radiofrequency Ablation for Low Back Pain (2012)


Connect with the Health Evidence and Policy unit:

Email: [email protected]

For questions or comments about Alberta Health Evidence Reviews, or if you have a health care delivery project or challenge that requires evidence and data, best practices, or an Alberta-specific solution tailored for optimum outcomes, contact us.

The Health Evidence and Policy unit manages the production of Alberta Health Evidence Reviews. The unit also supports the Alberta Advisory Committee on Health Technologies and works with partners across the health care system to build their capacity to produce and use evidence in decision-making.